The Department of Biological Sciences came out of the Biology Section in the Department of Basic Sciences under the Faculty of Education. The Section was established in 1999. It started offering courses in January 2000. The Biology Section was reconstituted into a stand-alone Biological Sciences Department in 2003. Its mandate then was to offer courses in biology and biology methodology to pre-service secondary school teachers. The Department also participated in in-service courses for serving secondary school biology teachers and conducted research in biological sciences, biology teaching/learning and related disciplines. After University–wide restructuring in 2016 the department relocated to the then newly formed Faculty of Science, Technology and Innovation.

The Department is endowed with a well-trained and dedicated staff to deliver adaptive curricular to learners that consist of courses blended with entrepreneurial thrusts in order to prepare learners for future careers and engagements. Currently, the Department is offering two unique undergraduate programs: the Bachelor of Science (Honours) in Parasitology and Disease Vector Control and Bachelor of Science (Honours) in Biodiversity and Conservation Management. In addition, it continues to service undergraduate programmes across the University. The department also offers two postgraduate programmes: the Master of Science in Biodiversity and Conservation Management and Doctor of Philosophy in Biological Sciences.